నైరూప్య

A Short Review on Schiff Bases and Applications

A R Rahimova*

Shiff bases are condentation of primary amines with carbonyl compounds and they were first reported by Schiff in 1864. The common structural feature of these compounds is the azomethine group with a general formula RHC=N-R1, where R and R1 are alkyl, aryl, cyclo alkyl or heterocyclic groups which may be variously substituted. These compounds are also knows as anils, imines or azomethines. Several studies showed that the prescence of a lone pair of electrons in an sp2 hybridized orbital of nitrogen atom of the azomethine is group of considerable chemical and biological importance. Because of the relative easiness of preparation, synthetic flexibility, and the special property of C=N group.